Научная тема: «ПРИОННЫЕ И НЕПРИОННЫЕ АМИЛОИДЫ: ИЗУЧЕНИЕ В ДРОЖЖЕВОЙ МОДЕЛИ»
Специальность: 03.00.03
Год: 2008
Отрасль науки: Биологические науки
Список опубликованных работ
1. Вишневская А.Б., Кушниров В.В., Тер-Аванесян М.Д. Нейродегенеративные амилоидозы: дрожжевая модель. Молекулярная биология. 2007. 41: 346-354.

2. Kushnirov,V.V., Salnikova,A.B., Alexandrov,I.M., and Ter-Avanesyan,M.D. 2007. Prion and non-prion amyloids: a comparison inspired by the yeast Sup35 protein. In: Protein-based inheritance, Y.O.Chernoff, ed. Landes Bioscience.

3. Bagriantsev SN, Kushnirov VV, Liebman SW. Analysis of amyloid aggregates using agarose gel electrophoresis. Methods Enzymol. 2006. 412: 33-48.

4. Kushnirov VV, Alexandrov IM, Mitkevich OV, Shkundina IS, Ter-Avanesyan MD. Purification and analysis of prion and amyloid aggregates. Methods. 2006. 39: 50-55.

5. Shkundina IS, Kushnirov VV, Tuite MF, Ter-Avanesyan MD. The Role of the N-Terminal Ologopeptide Repeats of the Yeast Sup35 Prion Protein in Propagation and Transmission of Prion Variants. Genetics. 2006; 172: 827-835.

6. Salnikova AB, Kryndushkin DS, Smirnov VN, Kushnirov VV, Ter-Avanesyan MD. Nonsense suppression in yeast cells overproducing Sup35 (eRF3) is caused by its non-heritable amyloids. J Biol. Chem. 2005. 280: 8808-8812.

7. Крындушкин Д.С., Александров И.М., Кушниров В.В., Тер-Аванесян М.Д. Дрожжи как модель для изучения прионов и амилоидов. Росс. Физиол. Журн. Им. И.М. Сеченова. 2004 90: 645-657.

8. Kryndushkin DS, Alexandrov IM, Ter-Avanesyan MD, Kushnirov VV. Yeast [PSI+] prion aggregates are formed by small Sup35 polymers fragmented by Hsp104. J Biol Chem. 2003. 278: 49636-49643.

9. Kryndushkin DS, Smirnov VN, Ter-Avanesyan MD, Kushnirov VV. Increased expression of Hsp40 chaperones, transcriptional factors, and ribosomal protein Rpp0 can cure yeast prions. J Biol Chem. 2002. 277: 23702-23708.

10. Chacinska A, Szczesniak B, Kochneva-Pervukhova NV, Kushnirov VV, Ter-Avanesyan MD, Boguta M. Ssb1 chaperone is a [PSI+] prion-curing factor. Curr Genet. 2001. 39: 62-67.

11. Kochneva-Pervukhova NV, Chechenova MB, Valouev IA, Kushnirov VV, Smirnov VN, Ter-Avanesyan MD. [PSI+] prion generation in yeast: characterization of the ´strain´ difference. Yeast. 2001. 18: 489-497.

12. Kushnirov VV, Kryndushkin DS, Boguta M, Smirnov VN, Ter-Avanesyan MD. Chaperones that cure yeast artificial [PSI+] and their prion-specific effects. Curr Biol. 2000. 10: 1443-1446.

13. Kushnirov VV. Rapid and reliable protein extraction from yeast. Yeast. 2000. 16: 857-860.

14. Kushnirov VV, Kochneva-Pervukhova NV, Chechenova MB, Frolova NS, Ter-Avanesyan MD. Prion properties of the Sup35 protein of yeast Pichia methanolica. EMBO J. 2000. 19: 324-331.

15. Тер-Аванесян М.Д., Кушниров В.В. Прионы: инфекционные белки с генетическими свойствами. Биохимия. 1999. 64: 1382-1390.

16. Kochneva-Pervukhova NV, Paushkin SV, Kushnirov VV, Cox BS, Tuite MF, Ter-Avanesyan MD. Mechanism of inhibition of [PSI+] prion determinant propagation by a mutation of the N-terminus of the yeast Sup35 protein. EMBO J. 1998. 17: 5805-5810.

17. Kushnirov VV, Ter-Avanesyan MD. Structure and replication of yeast prions. Cell. 1998. 94: 13-16.

18. Тер-Аванесян М.Д., Паушкин С.В., Кушниров В.В., Кочнева-Первухова Н.В. Молекулярные механизмы "белковой наследственности": прионы дрожжей. Мол. Биология. 1998. 32: 32-42.

19. Paushkin SV, Kushnirov VV, Smirnov VN, Ter-Avanesyan MD. In vitro propagation of the prion-like state of yeast Sup35 protein. Science. 1997. 277: 381-383.

20. Дагкесаманская А.Р., Кушниров В.В., Паушкин С.В., Тер-Аванесян М.Д. Присоединение глутатион S-трансферазы к N-концу дрожжевого белка Sup35p ингибирует его прионо-подобные свойства. Генетика. 1997. 33: 610-615.

21. Stansfield I, Kushnirov VV, Jones KM, Tuite MF. A conditional-lethal translation termination defect in a sup45 mutant of the yeast Saccharomyces cerevisiae. Eur J Biochem. 1997. 245: 557-563.

22. Paushkin SV, Kushnirov VV, Smirnov VN, Ter-Avanesyan MD. Interaction between yeast Sup45p (eRF1) and Sup35p (eRF3) polypeptide chain release factors: implications for prion-dependent regulation. Mol Cell Biol. 1997. 17: 2798-2805.

23. Derkatch IL, Chernoff YO, Kushnirov VV, Inge-Vechtomov SG, Liebman SW. Genesis and variability of [PSI+] prion factors in Saccharomyces cerevisiae. Genetics. 1996. 144: 1375-1386.

24. Paushkin SV, Kushnirov VV, Smirnov VN, Ter-Avanesyan MD. Propagation of the yeast prion-like [PSI+] determinant is mediated by oligomerization of the SUP35-encoded polypeptide chain release factor. EMBO J. 1996. 15: 3127-3134.

25. Stansfield I, Jones KM, Kushnirov VV, Dagkesamanskaya AR, Poznyakovski AI, Paushkin SV, Nierras CR, Cox BS, Ter-Avanesyan MD, Tuite MF. The products of the SUP45 (eRF1) and SUP35 genes interact to mediate translation termination in Saccharomyces cerevisiae. EMBO J. 1995. 14: 4365-4373.

26. Кушниров В.В., Тер-Аванесян М.Д., Смирнов В.Н. Структура и функциональное сходство дрожжевых белков Sup35 и Ure2 с прионами млекопитающих. Мол. Биология. 1995. 29: 750-755.

27. Ter-Avanesyan MD, Dagkesamanskaya AR, Kushnirov VV, Smirnov VN. The SUP35 omnipotent suppressor gene is involved in the maintenance of the non-Mendelian determinant [PSI+] in the yeast Saccharomyces cerevisiae. Genetics. 1994. 137: 671-676.

28. Ter-Avanesyan MD, Kushnirov VV, Dagkesamanskaya AR, Didichenko SA, Chernoff YO, Inge-Vechtomov SG, Smirnov VN. Deletion analysis of the SUP35 gene of the yeast Saccharomyces cerevisiae reveals two non-overlapping functional regions in the encoded protein. Mol Microbiol. 1993. 7: 683-692.

29. Kushnirov VV, Ter-Avanesyan MD, Didichenko SA, Smirnov VN, Chernoff YO, Derkach IL, Novikova ON, Inge-Vechtomov SG, Neistat MA, Tolstorukov II. Divergence and conservation of SUP2 (SUP35) gene of yeast Pichia pinus and Saccharomyces cerevisiae. Yeast. 1990. 6: 461-472.

30. Кушниров В.В., Тер-Аванесян М.Д., Дагкесаманская А.Р., Чернов Ю.О., Инге-Вечтомов С.Г., Смирнов В.Н. Делеционный анализ гена SUP2 (SUP35) дрожжей Saccharomyces cerevisiae. Мол. Биология. 1990. 24: 1037-1041.

31. Кушниров В.В., Тер-Аванесян М.Д., Смирнов В.Н., Чернов Ю.О., Деркач И.Л., Новикова О.Н., Инге-Вечтомов С.Г., Нейстат М.А., Толсторуков И.И. Сравнительный анализ структуры генов SUP2 (SUP35) дрожжей Pichia pinus и Saccharomyces cerevisiae. Мол. Биология. 1990. 24: 1024-1036.

32. Kushnirov VV, Ter-Avanesyan MD, Telckov MV, Surguchov AP, Smirnov VN, Inge-Vechtomov SG. Nucleotide sequence of the SUP2 (SUP35) gene of Saccharomyces cerevisiae. Gene. 1988. 66: 45-54.

33. Kushnirov VV, Ter-Avanesyan MD, Surguchov AP, Smirnov VN, Inge-Vechtomov SG. Localization of possible functional domains in SUP2 gene product of the yeast Saccharomyces cerevisiae. FEBS Lett. 1987. 215: 257-260.